Titanium dioxide nanoparticles modulate the toxicological response to cadmium in the gills of Mytilus galloprovincialis.

Camilla Della Torre,Teresa Balbi,Giacomo Grassi,Giada Frenzilli,Margherita Bernardeschi,Arianna Smerilli,Patrizia Guidi,Laura Canesi,Marco Nigro,Fabrizio Monaci,Vittoria Scarcelli,Lucia Rocco,Silvano Focardi,Marco Monopoli,Ilaria Corsi

Journal of Hazardous Materials（2015）

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摘要

•Nano-TiO2 modulate CdCl2 cellular responses in gills of marine mussel.•Nano-TiO2 reduced CdCl2-induced effects by lowering abcb1 m-RNA and GST activity.•Nano-TiO2 reduced Cd accumulation in mussel’s gills but not in whole soft tissue.•Higher accumulation of Ti in the presence of CdCl2 was observed in gills.

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关键词

Nano-TiO2,Cadmium,ABC transporters,Genotoxicity,NO production

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