Regulation of bitter taste responses by tumor necrosis factor.
Brain, Behavior, and Immunity(2015)
摘要
•TNF knockout mice are less sensitive to bitter compounds in taste behavioral tests.•TNF deficiency decreases gustatory nerve responses to bitter compounds.•TNFR1 and TNFR2 are both expressed in taste bud cells.•TNF regulates bitter taste responses through peripheral mechanisms.
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关键词
Cytokine,TNF,Inflammation,Taste-related behavior,Taste buds
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