Lung Cancer Screening The European Perspective

center dot Large randomized trials demonstrated that screening with low-dose computed tomography (CT) reduces mortality from lung cancer in active and former smokers. center dot Primary prevention with smoking cessation counseling improves cost-effectiveness of lung cancer screening. center dot Candidates should be selected according to estimation of lung cancer development risk. center dot Volumetric low-dose CT and fludeoxyglucose -PET can limit false positive rate and unnecessary invasive procedures. center dot Circulating biomarkers assessment and computer-assisted diagnosis software may further improve the accuracy and cost-effectiveness of lung cancer screening.