Toxoplasma gondii infection modulate systemic allergic immune response in BALB/c mice.

Experimental Parasitology(2015)

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摘要
•T. gondii immune-modulation at systemic level in an asthma mouse model.•Infection before allergic sensitization results in a lower Th2 cytokine response.•Sensitization during acute infection results in increased IFN-γ and TGF-β levels.•Infection results in a decreased T cell proliferation and anaphylaxis reaction.•T. gondii infection prevents an allergic reaction beyond the lung.
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关键词
Allergy,Toxoplasma gondii,Immune-modulation,Infection,Anaphylaxis
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