Tryptase is involved in the development of early ventilator-induced pulmonary fibrosis in sepsis-induced lung injury

Critical care (London, England), Volume 19, Issue 1, 2015, Pages 138-138.

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Abstract:

Most patients with sepsis and acute lung injury require mechanical ventilation to improve oxygenation and facilitate organ repair. Mast cells are important in response to infection and resolution of tissue injury. Since tryptase secreted from mast cells has been associated with tissue fibrosis, we hypothesized that tryptase would be invol...More

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