Physicochemical properties of pH-sensitive hydrogels based on hydroxyethyl cellulose-hyaluronic acid and for applications as transdermal delivery systems for skin lesions.
European Journal of Pharmaceutics and Biopharmaceutics（2015）
摘要
•Hydrogels composed of HEC and HA were developed.•Physicochemical properties of the hydrogel were determined by analysis equipment.•The hydrogel containing isoliquiritigenin effectively inhibited the growth of acne.•The HECHA hydrogels may have a potential applicability as a transdermal delivery system.
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关键词
pH-sensitive,Hydrogel,Smart hydrogel,Hyaluronic acid,Antimicrobial activity,Transdermal delivery system,Isoliquiritigenin,Propionibacterium acnes
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