Towards an HIV-1 cure: measuring the latent reservoir.

Katherine M Bruner,Nina N Hosmane,Robert F Siliciano

Trends in Microbiology（2015）

引用 166|浏览27

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摘要

•A high-throughput and well-validated assay is needed to accurately measure the HIV-1 LR.•PCR-based assays overestimate the size of the LR.•Culture-based assays underestimate the size of the LR.•No two HIV-1 eradication clinical trials use the same measurement.

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关键词

HIV-1,cure,latency,assays

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