Serum anti-tissue transglutaminase antibodies detected during febrile illness may not be produced by the intestinal mucosa.
The Journal of pediatrics(2015)
摘要
Anti-transglutaminase antibodies are the diagnostic marker of celiac disease, and are considered to be synthesized only by intestinal B-lymphocytes. During an infectious disease, these antibodies are transiently detected in serum. We show that these infection-triggered antibodies may not originate in the intestinal mucosa and are not an indication of celiac disease.
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