Clinical utility comparison of two benchtop deep sequencing instruments for rapid diagnosis of newly emergent influenza infections.

X Ren,Y Hu, F Yang,Y Xiao,L Li, J Dong, L Sun,Y Zhu,Q Jin

Clinical Microbiology and Infection（2015）

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摘要

Rapid determination of full genomes of influenza A viruses from clinical samples is vital to outbreak preparedness. We benchmarked Ion Torrent PGM and Illumina MiSeq to the standard Sanger sequencing on two real clinical samples and demonstrated their performance for full-genome determination and polymorphism identification.

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关键词

Deep sequencing,genome sequencing,influenza,Ion Torrent PGM,MiSeq

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