Remodeling of phospholipid composition in colon cancer cells by 1α,25(OH)2D3 and its analogs.

The Journal of Steroid Biochemistry and Molecular Biology(2015)

引用 11|浏览7
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摘要
•1,25(OH)2D3 and its analogs modulated the lipid profile of human colon cancer cells.•1,25(OH)2D3 and its analogs affected lipogenic gene expression in these cells.•Analogs mostly induced similar and more pronounced changes compared to 1,25(OH)2D3.•Changes in lipid profile after 1,25(OH)2D3/analog treatment were cell-line dependent.
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关键词
Vitamin D,Vitamin D analogs,Colon cancer,Phospholipid metabolism,Lipidomics
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