Estrogen receptor αlpha gene (ESR1) PvuII and XbaI polymorphisms are associated to metabolic and proinflammatory factors in polycystic ovary syndrome.

F S Silva,M O Sóter,M F Sales,Ana L Candido,Fernando M Reis,I F O Silva,Marinez O Sousa,Claudia N Ferreira,Karina Braga Gomes

Gene（2015）

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摘要

•ESR1 gene polymorphisms are not associated with PCOS development.•PvuII is associated with CRP, testosterone levels and waist circumference in PCOS.•XbaI is associated with fasting glucose in PCOS.•The polymorphisms are related to family history of hypertension or diabetes in PCOS.

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关键词

BMI,CRP,dNTP,ESR,FSH,HOMA,IGT,IR,LAP,LH,PCOS,T2DM,UFMG,WC

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