Development and validation of sensitive kinetic spectrophotometric method for the determination of moxifloxacin antibiotic in pure and commercial tablets.

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy(2015)

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摘要
•A novel kinetic method for analysis of moxifloxacin based on the reaction with MBTH was developed.•We found that acidic medium is necessary to success the spectrophotometric method.•The method validation demonstrated good recoveries and low detection limit.•The method was successfully applied for analysis of real pharmaceutical samples.
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关键词
Moxifloxacin,Kinetic spectrophotometry,3-Methyl-2-benzothiazolinone hydrazone hydrochloride monohydrate (MBTH),Tablets
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