Toxicogenomic markers for corticosteroid treatment in beef cattle: Integrated analysis of transcriptomic data

•This work reports an integrated analysis of DNA-microarray data from 146 bovine muscle samples (novel and previous data).•A robust gene expression signature for corticosteroid treatment in beef cattle was defined.•A Support Vector Machines classifier built on 73 biomarkers correctly classifies all the samples in the training set.•The predicted accuracy on new samples is 0.77 and false positive and false negative percentages are 5% and 6%, respectively.•A small set of genes can discriminate between controls and corticosteroid-treated animals, despite biological variation.