Synergistic effects of carboxymethyl-hexanoyl chitosan, cationic polyurethane-short branch PEI in miR122 gene delivery: accelerated differentiation of iPSCs into mature hepatocyte-like cells and improved stem cell therapy in a hepatic failure model.
Acta Biomaterialia(2015)
摘要
Crucial roles of amphiphilically modified chitosan CHC and miR122-iPSC-Heps in iPSC-Hep-based therapy for the treatment of fulminant hepatic failure.
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关键词
Induced pluripotent stem cells,miR122,Acute hepatic failure,Nano structured chitosan
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