Suspension of thymic emigration promotes the maintenance of antigen-specific memory T cells and the recall responses.

Ya-Nan Gao,Xiao-Yan Pei,Rong Jin,Chen Yin,Hui Shen,Xiu-yuan Sun,Qing Ge,Yu Zhang

Biochemical and Biophysical Research Communications（2014）

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摘要

•Timely decline in thymic output benefits memory T cells.•Thymic involution is important for protection against secondary infection.•Thymic involution may have a positive physiological significance.

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关键词

Thymic involution,Thymic emigrant,T cell homeostasis,Memory T cell,Thymectomy,Thymic grafting

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