Prognostic impact of COX-2 in non-small cell lung cancer: a comprehensive compartment-specific evaluation of tumor and stromal cell expression.

Johanna S M Mattsson,Bengt Bergman,Marianna Grinberg,Karolina Edlund,Millaray Marincevic,Karin Jirström,Fredrik Pontén,Jan G Hengstler,Jörg Rahnenführer,Mats G Karlsson,Christina Karlsson,Gisela Helenius,Johan Botling,Patrick Micke,Miklos Gulyas

Cancer Letters（2015）

引用 25|浏览19

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摘要

•COX-2 is frequently compartment specific expressed in human non-small cell lung.•COX-2 expression in tumor cells is not associated with prognosis.•COX-2 expression in stromal cells may have a prognostic impact.

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关键词

Cyclooxygenase 2,Lung cancer,PTGS2,Microarray,Prognosis,Immunohistochemistry

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