Total bile acids in the maternal and fetal compartment in relation to placental ABCG2 expression in preeclamptic pregnancies complicated by HELLP syndrome.

Jiska Jebbink,Geertruda Veenboer,Souad Boussata,Remco Keijser,Andreas E Kremer,Ronald Oude Elferink,Joris van der Post,Gijs Afink,Carrie Ris-Stalpers

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease（2015）

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摘要

•TBA levels in arterial and venous umbilical cord blood are similar.•TBA levels in maternal blood are increased in PE/HELLP pregnancy.•ABCG2 expression and protein levels are lower in PE/HELLP placenta.•ABCG2 expression does not correlate to either fetal or maternal TBA levels.

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关键词

Bile acids,Preeclampsia,HELLP

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