ABCD2 identifies a subclass of peroxisomes in mouse adipose tissue.

•We examined the D2 localization and the proteome of D2-containing compartment in mouse adipose tissue.•We confirmed the presence of D2 on a subcellular compartment that has typical structure as a microperoxisome.•We demonstrated the scarcity of peroxisome markers on D2-containing compartment.•The D2-containing compartment may be a subpopulation of peroxisome in mouse adipose tissue.•Proteomic data suggests potential association between D2-containing compartment and mitochondria and ER.