EURAMOS-1, an international randomised study for osteosarcoma: results from pre-randomisation treatment. J S Whelan , Stefan S Bielack , Neyssa Marina , Sigbjorn Smeland , Gordana Jovic , J M Hook , Mark Krailo , Jakob K Anninga , T Butterfassbahloul , T Bohling , G Calaminus , Marcello Capra , C Deffenbaugh , Catharina Dhooge , Mikael Eriksson , Adrienne M Flanagan , H Gelderblom , Allen M Goorin , Richard Gorlick , Georg Gosheger , R J Grimer , Kirsten Sundby Hall , K Helmke , Pancras C W Hogendoorn , Gernot Jundt , Leo Kager , T Kuehne , Ching C Lau , G D Letson , James S Meyer , Paul A Meyers , C Morris , H Mottl , Helen R Nadel , Rajaram Nagarajan , R L Randall , Paula J Schomberg , Roderich E Schwarz , Lisa A Teot , Matthew R Sydes , Mark Bernstein , J Pickering , Nicola Joffe , Matthias Kevric , B Sorg , Doojduen Villaluna , Caroline Wang , M Perisoglou , L Trani , Jenny Potratz , Dorothe Carrle , Miriam Wilhelm , Katja Zils , Carmen Teske Annals of Oncology（2015）
摘要
This manuscript describes the experience from registration until randomisation for a cohort of 2260 patients with osteosarcoma who joined the EURAMOS-1 trial. This includes pre-operative chemotherapy and surgery. It sets out the practical issues in collaboration and in achieving randomisation.
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关键词
osteosarcoma, randomised controlled trial, trial conduct, international collaboration
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