A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer Nina Schönhuber , Barbara Seidler , Kathleen Schuck , Christian Veltkamp , Christina Schachtler , Magdalena Zukowska , Stefan Eser , Thorsten B Feyerabend , Mariel C Paul , Philipp Eser , Sabine Klein , Andrew M Lowy , Ruby Banerjee , Fangtang Yang , Chang-Lung Lee , Everett J Moding , David G Kirsch , Angelika Scheideler , Dario R Alessi , Ignacio Varela , Allan Bradley , Alexander Kind , Angelika E Schnieke , Hans-Reimer Rodewald , Roland Rad , Roland M Schmid , Günter Schneider , Dieter Saur NATURE MEDICINE（2014）
摘要
The next generation of genetically engineered mouse models of pancreatic cancer involving a new inducible dual-recombinase system that combines Flp- FRT and Cre- loxP .
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nature medicine, science
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