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Discovery of 2-Pyridylpyrimidines As the First Orally Bioavailable GPR39 Agonists.

Stefan Peukert,Richard Hughes,Jill Nunez,Guo He,Zhao Yan,Rishi Jain,Luis Llamas,Sarah Luchansky,Adam Carlson,Guiqing Liang,Vidya Kunjathoor,Mike Pietropaolo,Jeffrey Shapiro,Anja Castellana,Xiaoping Wu,Avirup Bose

ACS Medicinal Chemistry Letters（2014）

引用 36|浏览16
关键词
sGPR39 agonists,GPR39 receptor,Zn2+-sensing receptor,antidiabetic treatment,fl-cell protection,GLP-I secretion,insulin secretion
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