Novel markers of gonadectomy-induced adrenocortical neoplasia in the mouse and ferret.

Maximiliaan Schillebeeckx,Marjut Pihlajoki,Elisabeth Gretzinger,Wei Yang,Franziska Thol,Theresa Hiller,Ann-Kathrin Löbs,Theresa Röhrig,Anja Schrade,Rebecca Cochran,Patrick Y Jay,Markku Heikinheimo,Robi D Mitra,David B Wilson

Molecular and Cellular Endocrinology（2015）

引用 22|浏览12

暂无评分

摘要

•Spinlw1, Insl3, & Foxl2 are upregulated in murine post-GDX adrenocortical tumors.•FOXL2 immunoreactivity is evident in adrenocortical tumors from gonadectomized ferrets.•Igfbp6 and Foxs1 are hypomethylated and upregulated in murine post-GDX adrenocortical tumors.•Post-GDX adrenocortical tumors exhibit properties of female and male gonadal cells.

查看译文

关键词

Adrenal cortex,Endocrine tumor,Gonadotropin,Ovariectomy,Steroidogenesis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要