Changes in total and central fat mass after a hypocaloric diet associate with changes of apoC-I in postmenopausal obese women.

►Postmenopausal healthy obese women were studied.►Baseline apolipoprotein concentrations did not correlate with fat mass.►Baseline apolipoprotein concentrations did not correlate with insulin sensitivity.►Hypocaloric diet did not significantly change plasma lipids.►Hypocaloric diet did not significantly change apolipoprotein concentrations.►Weight loss–induced changes of central fat mass correlated with changes of apoC-I.