5,7,3',4'-Tetramethoxyflavone exhibits chondroprotective activity by targeting β-catenin signaling in vivo and in vitro.

Longhuo Wu,Haiqing Liu,Linfu Li,Hai Liu,Kai Yang,Zhaowen Liu,Hao Huang

Biochemical and Biophysical Research Communications（2014）

引用 16|浏览18

暂无评分

摘要

•PGE2 increased the expression of cAMP/PKA signaling pathway in chondrocytes.•PGE2 activated the expression of β-catenin signaling pathway.•TMF down regulated EP/cAMP/PKA and β-catenin signaling pathways.•TMF is a potential compound with chondroprotective activity.

查看译文

关键词

5,7,3′,4′-Tetramethoxyflavone,Osteoarthritis,Chondrocytes,β-Catenin,PGE2

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要