Increased fracture risk in patients with type 2 diabetes mellitus: an overview of the underlying mechanisms and the usefulness of imaging modalities and fracture risk assessment tools.

Maturitas(2014)

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摘要
•An increased falling frequency and a decreased bone quality contribute to the increased fracture risk in T2DM patients.•DXA and FRAX® can be used to assess fracture risk in T2DM patients, but they both underestimate the absolute fracture risk.•HR-pQCT is a promising new imaging modality.
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关键词
AGE,aBMD,BMD,BMI,DPP-4,DXA,eBMD,GLP-1,HbA1c,PPAR-γ,PTH,SGLT2,T2DM,TZD,vBMD,WHO
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