Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis.

Larissa Lipskaia,Zela Keuylian,Karl Blirando,Nathalie Mougenot,Adeline Jacquet,Clotilde Rouxel,Haifa Sghairi,Ziane Elaib,Regis Blaise,Serge Adnot,Roger J Hajjar,Elie R Chemaly,Isabelle Limon,Regis Bobe

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research（2014）

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摘要

The sarco(endo)plasmic reticulum Ca2+ATPases (SERCA) system, a key regulator of calcium cycling and signaling, is composed of several isoforms. We aimed to characterize the expression of SERCA isoforms in mouse cardiovascular tissues and their modulation in cardiovascular pathologies (heart failure and/or atherosclerosis).

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关键词

Ca2+ATPase,SERCA,Calcium signaling,Cardiovascular,Heart,Smooth muscle cells

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