Alleviation of severe inflammatory responses in LPS-exposed mice by Schisantherin A.

Dan Li,Xinxin Ci,Yang Li,Chaoying Liu,Zhongmei Wen,Jing Jie,Liping Peng

Respiratory Physiology & Neurobiology（2014）

引用 13|浏览9

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摘要

•Schisantherin A attenuated pulmonary damage in LPS-induced ALI model.•Schisantherin A decreased lung inflammatory response to LPS in ALI model.•Schisantherin A improved survival rate of mice challenged by LPS.•Schisantherin A blocked MAPKs and NF-κB pathways activation in LPS-induced ALI model.

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关键词

Schisantherin A,LPS,ALI,MAPKs,NF-κB

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