Promoter analysis of the gene encoding GDNF in murine Sertoli cells.

Molecular and Cellular Endocrinology(2014)

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摘要
•First characterization of murine GDNF promoter region in Sertoli cells.•Identification of the transcriptional start sites.•In-silico analysis of evolutionarily conserved putative transcription factor-binding sites.•Performed progressive promoterdeletions.•Identification of three CRE sites involved in basal and cAMP-induced expression.
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关键词
GDNF,FSH,Sertoli cells,Luciferase activity,CRE,Spermatogonial stem cells
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