Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro.

Kirti Kumar Tiwari,Chun Chu,Xanthi Couroucli,Bhagavatula Moorthy,Krithika Lingappan

Biochemical and Biophysical Research Communications（2014）

引用 47|浏览3

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摘要

•Caffeine at 0.05mM decreases oxidative stress in hyperoxia.•Caffeine at 1mM decreases cell viability, increases oxidative stress in hyperoxia.•Caffeine at 1 but not 0.05mM, abrogates hyperoxia-induced G2/M arrest.

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关键词

BPD,RDS,ROS

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