Placental antiangiogenic prolactin fragments are increased in human and rat maternal diabetes.

P Perimenis,T Bouckenooghe,J Delplanque,E Moitrot,E Eury,S Lobbens,P Gosset,L Devisme,B Duvillie,A Abderrahmani,L Storme,P Fontaine,P Froguel,A Vambergue

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease（2014）

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摘要

•Placental role in diabetic mothers on fetal development is unknown.•Vasoinhibins may participate to placental dysfunction in diabetes mellitus.•Levels of PRL family members are modified in the placenta during maternal diabetes.•Placental changes of the PRL family members could impact on fetal development.

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关键词

BMP-1,CTSD,D,dPRL,DPRP,DT1,IUGR,MD,MMP,NCT,PAS,PRL,RIN,SGA,STZ

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