Applications Of Pressure Control Ventilation Volume Guaranteed During One-Lung Ventilation In Thoracic Surgery

Objective: To explore the effects of ventilatory mode "pressure controlled ventilation-volume guaranteed" (PCV-VG) on the inspiratory pressures, oxygenation parameters and hemodynamics of patients during one lung ventilation (OLV) for thoracic surgery, compared with volume controlled ventilation (VCV). Methods: Twenty participants were recruited and equally assigned into two groups in a controlled, randomized, crossover design. Group A: VCV was performed initially and changed into PCV-VG after 30 min; Group B: In the reverse order. Blood gas analysis, peak inspiratory pressure (Ppeak), mean inspiratory pressure (Pmean), plateau inspiratory pressure (Plateau) were measured at four different time points: (1) 30 min after total lung ventilation (TLV); (2) 30 min after one lung ventilation (VCV or PCV-VG); (3) 30 min after shifting to the other ventilatory mode, and (4) 30 min after reconstruction of TLV. Results: The Ppeak, Plateau, and Pmean were significantly lower in PCV-VG compared with VCV. There was significant increase in arterial partial pressure of oxygen under PCV-VG. Conclusion: In patients undergoing thoracic surgery with OLV, pressure controlled volume guaranteed mode of ventilation may have better effects by decreasing inspiratory pressure parameters and improving arterial oxygenation than volume controlled ventilation.