Expression and immunogenic analysis of recombinant polypeptides derived from capsid protein VP1 for developing subunit vaccine material against hepatitis A virus.

Kyoung Ok Jang,Jong-Hwa Park,Hyun Ho Lee,Dae Kyun Chung,Wonyong Kim,In Sik Chung

Protein Expression and Purification（2014）

引用 6|浏览3

暂无评分

摘要

•Recombinant VP1-His, VP1-3N-His, and 3D2-Hiswere produced in Escherichia coli.•Recombinant polypeptides elicited the titers of specific IgG antibodies in sera.•The highest neutralizing activity was shown in sera from VP1-3-N-His-immunized mice.

查看译文

关键词

Antigenicity,Capsid protein VP1,Hepatitis A,Hepatitis A virus,Neutralizing activity,Recombinant polypeptides

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要