Synthesis, in vitro antimicrobial and cytotoxic activities of novel pyrimidine-benzimidazol combinations.

Peng-Ju Chen,Ang Yang,Yi-Fei Gu,Xiao-Song Zhang,Kun-Peng Shao,Deng-Qi Xue,Peng He,Teng-Fei Jiang,Qiu-Rong Zhang,Hong-Min Liu

Bioorganic & Medicinal Chemistry Letters（2014）

引用 46|浏览11

暂无评分

摘要

Compounds 7a and 7b exhibited enhanced cytotoxic activities against MGC-803 in vitro, when compared to 5-Fu. The activities of compounds 7b and 7c against Stenotrophomonas maltophilia, which is rather drug resistant species, with the MIC of 2μg/ml and 4μg/ml.

查看译文

关键词

Pyrimidine,Benzimidazole,Synthesis,Antimicrobial,Cytotoxic activities

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要