Development and immunological evaluation of HLA-specific chronic myeloid leukemia polyepitope vaccine in Chinese population.

Wenhao Dong,Jingru Zhang,Na Shao,Tian Tian,Lu Li,Jimo Jian,Shaolei Zang,Daoxin Ma,Chunyan Ji

Vaccine（2014）

引用 5|浏览15

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摘要

•We construct a novel chronic myeloid leukemia polyepitope dentritic cell (DC) vaccine (DC-BCR/ABL*WT1).•DC-BCR/ABL*WT1 is more specific to Chinese population.•DC-BCR/ABL*WT1 demonstrates strong immune response to BCR/ABL(+) patients.

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关键词

Chronic myeloid leukemia,Polyepitope vaccine,Dentritic cell,Chinese population

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