Natural killer (NK)-like cytotoxicity of murine intraepithelial lymphocytes in the small intestine (iIEL) and the effect of the serine proteases.
MICROBIOLOGY AND IMMUNOLOGY(1995)
摘要
The natural killer (NK)-like cytotoxicity of murine intraepithelial lymphocytes in the small intestine (iIEL) and the participation of serine proteases in it were investigated, We monitored the cytotoxicity of iIEL with a sensitive cytotoxic assay using laser how cytometry. iIEL exhibited NK-like cytotoxicity on YAC-1 target cells, Benzamidine, a serine protease inhibitor, inhibited significantly both Na-CBZ-L-lysine thiobenzyl ester (BLT)-specific serine protease activity and iIEL-mediated NK-like cytotoxicity. These results suggest that BLT-specific serine proteases may participate in NK-like cytotoxicity of murine iIEL.
更多查看译文
关键词
IIEL,NK ACTIVITY,SERINE PROTEASE,BENZAMIDINE
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要