Analysis of essential pathways for self-renewal in common marmoset embryonic stem cells.

Takenobu Nii,Tomotoshi Marumoto,Hirotaka Kawano,Saori Yamaguchi,Jiyuan Liao,Michiyo Okada,Erika Sasaki,Yoshie Miura,Kenzaburo Tani

FEBS Open Bio（2014）

引用 11|浏览6

暂无评分

摘要

•Self-renewal of common marmoset embryonic stem cells (CM ESCs) is promoted by bFGF.•bFGF activates the PI3K-AKT pathway in CM ESCs on feeder cells.•bFGF and TGFβ in combination support culture of CM ESCs without feeder cells.•CM ESCs show phenotypes similar to those of human ESCs and mouse epiblast SCs.

查看译文

关键词

AKT,bFGF,CM,EB,EpiSCs,ERK,ESCs,FCM,iPSCs,JAK,KSR,LIF,MEFs,MEK,PI3K,RT-PCR,SMAD2/3,STAT3,TGFβ

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要