The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2/4 in vivo.

Mengyun Ke,Hui Wang,Min Zhang,Yuwei Tian,Yizhou Wang,Bing Li,Jie Yu,Jie Dou,Tao Xi,Changlin Zhou

Biochemical Pharmacology（2014）

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摘要

SEP inhibited lung cancer growth through activating NK and T cells via TLR2/4, and the activated-immune cells secreted effectors, such as perforin and IFN-γ.

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关键词

SEP,Lung cancer,Natural killer cell,TLR,Immunotherapy

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