Metabonomic study of Wu-tou decoction in adjuvant-induced arthritis rat using ultra-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry.
Journal of Chromatography B(2014)
摘要
•WTD exhibited good anti-inflammatory and antioxidant activities in AIA rat.•A urinary metabonomics method by UPLC-Q-TOF-MS was used to study the efficacy of WTD.•Sixteen Eleven potential biomarkers in response to WTD treated for AIA rats had been identified.•The biological meanings of the potential biomarkers were discussed.
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关键词
Wu-tou decoction,Metabonomics,Mass spectrum,Adjuvant-induced arthritis,Traditional Chinese medicine
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