Molecular epidemiology of merkel cell polyomavirus: evidence for geographically related variant genotypes.

Claire Martel-Jantin,Claudia Filippone,Patricia Tortevoye,Philippe V Afonso,Edouard Betsem,Stéphane Descorps-Declere,Jérôme T J Nicol,Antoine Touzé,Pierre Coursaget,Maryse Crouzat,Nicolas Berthet,Olivier Cassar,Antoine Gessain

JOURNAL OF CLINICAL MICROBIOLOGY（2014）

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摘要

Merkel cell polyomavirus (MCPyV) is linked to a cutaneous cancer mainly occurring in Caucasians. DNA from skin swabs of 255 adults, originating from the 5 continents, were subjected to MCPyV PCRs. Phylogenetic analyses demonstrate the existence of 5 major geographically related MCPyV genotypes (Europe/North America, Africa [sub-Saharan], Oceania, South America, and Asia/Japan).

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