A molecular analysis of quinolone-resistant haemophilus influenzae: Validation of the mutations in quinolone resistance-determining regions

Hisashi Shoji,Tetsuro Shirakura,Takahiro Takuma,Kazuo Tanaka,Kunihiko Fukuchi,Yoshihito Niki

Journal of Infection and Chemotherapy（2013）

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摘要

The mechanism of quinolone-resistance is considered to be amino acid mutations in the type II topoisomerase. We validated the genetic mechanisms of quinolone resistance in Haemophilus influenzae.

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Bacteria,Infections,Molecular pathology

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