Nociception and inflammatory hyperalgesia evaluated in rodents using infrared laser stimulation after Trpv1 gene knockout or resiniferatoxin lesion.

Kendall Mitchell,Evan E Lebovitz,Jason M Keller,Andrew J Mannes,Michael I Nemenov,Michael J Iadarola

PAIN®（2014）

引用 56|浏览9

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摘要

Chemoablation of TRPV1-containing afferent fibers with resiniferatoxin produces more profound analgesia than TRPV1 receptor knockout assessed using either Aδ- or C-fiber stimulation during baseline or inflamed conditions.

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关键词

Nociception,Analgesia,Chemoreceptors,Chronic Pain,Capsaicin

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