Validation of NCM460 cell model as control in antitumor strategies targeting colon adenocarcinoma metabolic reprogramming: trichostatin A as a case study.

Gema Alcarraz-Vizán,Susana Sánchez-Tena,Mary Pat Moyer,Marta Cascante

Biochimica et Biophysica Acta (BBA) - General Subjects（2014）

引用 13|浏览2

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摘要

•NCM460 cells exhibit a characteristic non-tumor metabolic profile•TSA-induced HT29 cell differentiation reverts its tumor metabolic profile•NCM460 cells maintain its metabolic homeostasis in response to TSA treatment

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关键词

Colon cancer,Glycolysis,Metabolic adaptation,Metabolic profile,Tumour metabolism,Trichostatin-A

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