Biomimetic nanocomposites of carboxymethyl cellulose-hydroxyapatite: novel three dimensional load bearing bone grafts.
Colloids and Surfaces B: Biointerfaces（2014）
摘要
•Synthesized a biomimetic 3D porous CMC–HA nanocomposites.•The CMC controls the HA particles size in the range of 15–50nm.•Self assembly assists the formation of mechanically strong (2–12MPa) 3D structure.•Ionic/polar interaction is the key for formation of 3D porous nanocomposites.•Nanocomposites are cytocompatible for bone marrow mesenchymal cells.
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关键词
Biomimetic materials,Bone graft,Cellulose,Polymer–hydroxyapatite nanocomposite,Biopolymer
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