Estrogen modulates cardiac growth through an estrogen receptor α-dependent mechanism in healthy ovariectomized mice.

Georgios Kararigas,Ba Tiep Nguyen,Hubertus Jarry

Molecular and Cellular Endocrinology（2014）

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摘要

•Ovariectomy, ERα or ERβ deletion did not affect food intake.•Estrogen modulates postnatal cardiac growth in healthy mice via ERα.•ERα is necessary for E2 to induce transcription of Igf1 and Myocd.

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关键词

Estrogen,Estrogen receptor,Heart

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