Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.

Sheryl S Moy,Natallia V Riddick,Viktoriya D Nikolova,Brian L Teng,Kara L Agster,Randal J Nonneman,Nancy B Young,Lorinda K Baker,Jessica J Nadler,James W Bodfish

Behavioural Brain Research（2014）

引用 54|浏览24

暂无评分

摘要

•The C58/J inbred mouse strain was supersensitive to locomotor effects of amphetamine.•Both C58/J and Grin1 knockdown mice had overt deficits in the marble-burying task.•C58/J had reduced exploration and altered olfactory preference in a nose-poke test.•Strain genome comparisons identified 97 autism candidate genes divergent in C58/J.

查看译文

关键词

Autism spectrum disorder,Circumscribed interests,Hyperactivity,NMDA receptor,Olfaction,SNP analysis

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要