Discovery and Optimization of Orally Active Cyclohexane-Based Prolylcarboxypeptidase (prcp) Inhibitors
John S. Debenham,Thomas H. Graham,Andreas Verras,Yong Zhang,Matthew J. Clements,Jeffrey T. Kuethe,Christina Madsen-Duggan,Wensheng Liu,Urmi R. Bhatt,Dunlu Chen,Qing Chen,Margarita Garcia-Calvo,Wayne M. Geissler,Huaibing He,Xiaohua Li,JeanMarie Lisnock,Zhu Shen,Xinchun Tong,Elaine C. Tung,Judyann Wiltsie,Suoyu Xu,Jeffrey J. Hale,Shirly Pinto,Dong-Ming Shen Bioorganic & Medicinal Chemistry Letters（2013）
关键词
PrCP,Prolylcarboxypeptidase,Serine protease,Inhibitor,Obesity
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