Recombinant Ehrlichia P29 protein induces a protective immune response in a mouse model of ehrlichiosis.

Nagaraja R Thirumalapura,Patricia A Crocquet-Valdes,Tais B Saito,Sunil Thomas,Jere W McBride,David H Walker

Vaccine（2013）

引用 7|浏览5

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摘要

•Immunization with recombinant E. muris P29 induced protective immune responses.•Protection induced by rP29 was associated with development of IgG antibodies.•P29-specific effector/memory CD4+ Th1 responses induced during E. muris infection.

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关键词

Ehrlichia,Intracellular bacteria,Vaccine,Protective immunity,Antigen,Antibody

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