Caspase-mediated cleavage and DNase activity of the translation initiation factor 3, subunit G (eIF3g)

Jong-Tae Kim,Seon-Jin Lee,Bo-Yeon Kim,Chul-Ho Lee,Young Il Yeom,Yong-Kyung Choe,Do-Young Yoon,Suhn-Kee Chae,Jung Woo Kim,Young Yang,Jong-Seok Lim,Hee Gu Lee

FEBS Letters（2013）

引用 8|浏览4

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摘要

•eIF3g is cleaved at SLRD220G by caspase-3 and -7 during apoptosis.•The cleaved N-terminus of eIF3g translocates to the nucleus.•The N-terminus of eIF3g exhibits DNase activity.

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关键词

Translation initiation factor,eIF3g,Caspase,DNase,Apoptosis

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