Molecular basis for homo-dimerization of the CIDE domain revealed by the crystal structure of the CIDE-N domain of FSP27.
Biochemical and Biophysical Research Communications（2013）
摘要
•We solved the crystal structure of CIDE-N domain of FSP27.•CIDE-N domain of FSP27 was dimer in solution and dimeric structure was solved.•We provide the information of homo-dimeric interface formed by the CIDE domain.•Our structure revealed that homo-dimerization mechanism that might be important for the function of FSP27.
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关键词
Apoptosis,Energy metabolism,FSP27,Crystal structure,CIDE domain
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