Effect Of Treatment With A Combination Of 6-Mercaptopurine And Porfiromycin On An Established Friend Leukemia Virus Infection

CANCER RESEARCH(1969)

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the effect of parenteral therapy with combinations of 6- mercaptopurine and porfiromycin on established infections of friend leukemia virus in swiss mice was studied. in one experi ment both drugs were markedly effective in reducing virus induced splenomegaly and virus titers in the plasma and spleens,when comparative nonlethal drug levels were used. in a second experiment these results we,but treatment with the combination of drugs was more effective than treatment with either drug used alone
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